acid alpha toxin alternative energy aspartic acid bacteria biological membrane biotechnology blood cell biology cell signaling chemical bond cholesteryl ester storage disease chymotrypsin colipase digital object identifier endothelial lipase endothelium enzyme ester esterase extracellular fat fatty acid gastric lipase gene gene duplication genetics glycerol hepatic lipase histidine hormone-sensitive lipase human hydrolysis inflammation intracellular lingual lipase lipid lipoprotein lipoprotein lipase lipoprotein lipase deficiency lysosomal lipase lysosome mammal medical subject headings monoglyceride mutation nucleophile oil organelle organism orientations of proteins in membranes database pancreas pancreatic lipase peripheral membrane protein phospholipase phospholipase a phospholipase c phospholipid protein data bank protein folding serine triglyceride triglyceride lipase virus wolman disease